What is AHCC?
AHCC (Active Hexose Correlated Compound) is a unique and powerful extract derived from the mycelium of shiitake mushrooms. This proprietary compound has been extensively researched for its potential to support immune system function and overall wellness.
Through a specialized cultivation and extraction process, AHCC provides a rich source of alpha-glucans, which are believed to play a key role in supporting the body's natural defenses.
A Multi-Stage Fermentation Process
Rather than using simple dried mushroom powder, AHCC® undergoes a carefully controlled cultivation process. The mycelium is cultivated, fermented, concentrated, and gently freeze-dried at each stage to preserve its bioactive integrity.
A Unique Bioactive Profile
This process yields a composition rich in alpha-glucans and naturally occurring oligosaccharides — compounds that distinguish AHCC® from conventional mushroom extracts and underpin its use in scientific research.
From Shiitake Mycelium to AHCC®
The graphic illustrates the multi-step cultivation and production process used to create AHCC® from Lentinula edodes (shiitake) mycelium.
The process begins with a carefully selected shiitake mycelium culture, which is preserved as a frozen working culture to ensure consistency and purity throughout production.
The mycelium is then gradually expanded through several cultivation stages:
- shaking culture
- aeration culture
- pre-culture
- and finally large-scale main culture fermentation tanks
During this controlled cell culture process, the mycelium grows under optimized conditions that support the development of characteristic AHCC® alpha-glucans and other naturally occurring compounds.
After cultivation, the material undergoes separation and concentration steps before being gently freeze-dried. The final stage includes powdering and granulation, resulting in the finished AHCC® extract used in supplements and research applications.
This carefully standardized production method helps ensure batch-to-batch consistency and distinguishes AHCC® from conventional mushroom powders or simple extracts.

